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This damage causes a backflow of bile into the liver

The level of GSH/GSSG in the cells treated with NS for more than 6 h was also significantly decreased, but the extent was smaller than that in the NSBSO group, indicating that the combination of consumption of existing GSH and inhibition of GSH synthesis promotes the exhaustion of GSH in cells

Figure 1 Vaccinating mice with CspZ, VLP-CspZ, or VLP-CspZ-Y207A/Y211A induced similar levels of anti-CspZ antibodies

"Glutathione and Omega-3: A Comprehensive Review of Their Combined Effects on Oxidative Stress and Inflammation." International Journal of Molecular Sciences, 23(7), 3756.